Elacestrant-d4-1

Elacestrant-d4-1 is the deuterium labeled Elacestrant. Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively[1][2].

C30H34D4N2O2

462.66

OC1=C([2H])C=C2C[C@H](C3=CC([2H])=C(OC)C([2H])=C3N(CC)CC4=CC=C(CCNCC)C=C4)CCC2=C1[2H]

Estrogen Receptor/ERR; Isotope-Labeled Compounds

10 mM in DMSO

Room temperature