Elenestinib (phosphate) [CAS 2832013-93-9]

Elenestinib (BLU-263) phosphate is an orally active inhibitor of Tyrosine kinase with an IC50 of 0.2 nM for KIT D816V. Elenestinib phosphate minimally penetrates the blood-brain barrier. Elenestinib phosphate can be used in the study of systemic mastocytosis[1][2].

[2832013-93-9]

C27H32FN10O5P

626.58

OCCN1C=C(C=N1)C2=CN3N=CN=C(N4CCN(C5=NC=C([C@@](N)(C6=CC=C(C=C6)F)C)C=N5)CC4)C3=C2.OP(O)(O)=O

C-Kit

10 mM in DMSO

Room temperature