(-) -Eleutherin [CAS 22768-95-2]

(-) -Eleutherin is a pyranonaphthoquinone derivative that exhibits cytotoxic activity by inhibiting DNA topoisomerase II. (-) -Eleutherin has been shown to have promising potential as a medicinal compound due to its association with naphthoquinones. (-) -Eleutherin demonstrates significant DNA fragmentation rates, indicating its strong cytotoxic effects on cells. Additionally, (-) -Eleutherin possesses higher antioxidant potential compared to control samples, contributing to its therapeutic efficacy.

[22768-95-2]

C16H16O4

272.3

O=C1C2=C(OC)C=CC=C2C(C3=C1[C@@H](O[C@@H](C3)C)C)=O

Topoisomerase

Room temperature