Elisrasib [CAS 2914919-85-8]

Name: Elisrasib [CAS 2914919-85-8]
Brand: QuantiMol
SKU: QM-0075846-01
Price: 834.89 GBP
Availability: InStock

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SKU:QM-0075846-01

£834.89 GBP

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Product Details

Description
Elisrasib is an orally active inhibitor for KRAS. Elisrasib inhibits the proliferation of KRASG12C mutant H358 and MIA-PA-CA-2 with an IC50 of 0.6 and 0.44 nM. Elisrasib exhibits good metabolic stability in hepatocytes, liver microsomes, plasma and whole blood in various species. D3S-001 exhibits good pharmacokinetic characteristics and antitumor efficacy in mice[1].
CAS Number
[2914919-85-8]
Molecular Formula
C32H35F6N7O3
Molecular Weight
679.66
Smiles
FC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Target
Ras
Purity
98.5
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0075846-01	1 mgQM-0075846-01 £834.89/ea	£0.00	Quantity	£834.89/ea	£0.00

5 mgQM-0075846-02	5 mgQM-0075846-02 £2,008.58/ea	£0.00	Quantity	£2,008.58/ea	£0.00

10 mgQM-0075846-03	10 mgQM-0075846-03 £3,188.34/ea	£0.00	Quantity	£3,188.34/ea	£0.00

25 mgQM-0075846-04	25 mgQM-0075846-04 £6,325.48/ea	£0.00	Quantity	£6,325.48/ea	£0.00

50 mgQM-0075846-05	50 mgQM-0075846-05 £10,091.98/ea	£0.00	Quantity	£10,091.98/ea	£0.00

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Elisrasib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.