ELOVL6-IN-4 [CAS 1170321-92-2]

ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3[1].

[1170321-92-2]

C20H20F3N3O3S

439.45

FC(F)(F)C(C=C1)=CC=C1NC(N2[C@@]3([H])C[C@@H](C[C@]2([H])CC3)S(=O)(C4=CC=CC=N4)=O)=O

ELOVL

98.36

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature