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Eltanexor Z-isomer [CAS 1642300-78-4]
Eltanexor Z-isomer [CAS 1642300-78-4]
SKU:QM-0079304-01
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Product Details
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Description
Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. IC50: In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, 30 μM, respectively[1]. In Vivo:
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CAS Number
[1642300-78-4]
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Molecular Formula
C17H10F6N6O
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Molecular Weight
428.29
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Smiles
O=C(N)/C(C1=CN=CN=C1)=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
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Target
CRM1
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Purity
95.98
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Eltanexor Z-isomer [CAS 1642300-78-4]
Eltanexor Z-isomer is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.