Emodin-8-glucoside [CAS 23313-21-5]

Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC50s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier[1][2][3][4][5].

[23313-21-5]

C21H20O10

432.38

O=C1C2=C(C=C(C)C=C2O)C(C3=CC(O)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C13)=O

Aldose Reductase; p38 MAPK; SOD; Topoisomerase

99.35

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, protect from light)

Room Temperature

H302

H302