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Endoxifen-d5 (Z-isomer) [CAS 1584173-54-5]
Endoxifen-d5 (Z-isomer) [CAS 1584173-54-5]
SKU:QM-0016474
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Product Details
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Description
Endoxifen-d5 (Z-isomer) is the deuterium labeled Endoxifen (Z-isomer). Endoxifen (Z-isomer) is an oral active Tamoxifen (HY-13757A) metabolite, inducing an anti-estrogenic effect in breast cancer cells expressing ERα. Endoxifen (Z-isomer) inhibits hERG. This effect is concentration-dependent, with an IC50 value of 1.6 μM[1][2][3][4].
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CAS Number
[1584173-54-5]
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Molecular Formula
C25H22D5NO2
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Molecular Weight
378.52
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Smiles
[2H]C([2H])([2H])C([2H])([2H])/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)O)/C3=CC=C(C=C3)OCCNC
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Target
Cytochrome P450; Drug Metabolite; Estrogen Receptor/ERR; Isotope-Labeled Compounds; Parasite
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Shipping Conditions
Room temperature
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Endoxifen-d5 (Z-isomer) [CAS 1584173-54-5]
Endoxifen-d5 (Z-isomer) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.