Enopeptin A [CAS 139601-96-0]

Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC=25 μg/mL), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs=200 μg/mL) ; however, it is not inhibitory to fungi.

[139601-96-0]

C47H57N7O11

896

[FSPAAP(Lactonebridge:Ser2-Pro6)]

Antibiotic; Bacterial

Room temperature