1 1

Epiberberine [CAS 6873-09-2]

Epiberberine [CAS 6873-09-2]

Size

QM-0162292-01

£129.63 GBP
Sale Sold out

Request quote or documents

View full details

Product Details

  • Description

    Epiberberine is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and can be used for the research of Alzheimer disease[1]. Epiberberine inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways[2]. Epiberberinecan be used for the research of diabetic disease[3].

  • CAS Number

    [6873-09-2]

  • Molecular Formula

    C20H18NO4+

  • Molecular Weight

    336.36

  • Smiles

    COC1=C(OC)C=C2C(CC[N+]3=C2C=C(C=C4)C(C5=C4OCO5)=C3)=C1

  • Target

    Beta-secretase; Cholinesterase (ChE)

  • Isoform

    AChE; BACE1; BChE

  • Purity

    98.46

  • Solubility

    DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Learn more
Variant Variant total Quantity Price Variant total
5 mgQM-0162292-01
5 mgQM-0162292-01
£129.63/ea		 £0.00
£129.63/ea £0.00
10 mgQM-0162292-02
10 mgQM-0162292-02
£200.66/ea		 £0.00
£200.66/ea £0.00
50 mgQM-0162292-03
50 mgQM-0162292-03
£602.83/ea		 £0.00
£602.83/ea £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

Epiberberine [CAS 6873-09-2]

Epiberberine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.