ER degrader 2 [CAS 2390147-41-6]

ER degrader 2 is a potent degrader of estrogen receptor (ER) . The estrogen signaling system plays an important role in regulating cell growth, differentiation and apoptosis. ER degrader 2 has the potential for the research of cancer diseases (extracted from patent CN112830919A, compound 1) [1].

[2390147-41-6]

C34H42F3N5O3

625.72

CC(C)(F)CN1[C@@](C2=C(C=C(C=C2F)OCCNC/C=C/C(N3CCOCC3)=O)F)([H])C4=CC=C(C5=CN(N=C5)C)C=C4C[C@H]1C

Estrogen Receptor/ERR

10 mM in DMSO

Room temperature