ER degrader 9 [CAS 3023359-75-0]

ER degrader 9 (compound 1), a bifunctional molecular glue, is a potent estrogen receptor (ER) degrader with a DC50 of ≤10 nM in MCF-7 cells. ER degrader 9 can be used for the research of breast cancer[1].

[3023359-75-0]

C40H48N4O2

616.83

CC(C)(/C=C(C(N1CCN(CC1)CC2CCN(CC2)C3=CC=C(C=C3)[C@H]4[C@H](CCC5=CC(O)=CC=C54)C6=CC=CC=C6)=O)/C#N)C

Estrogen Receptor/ERR; Molecular Glues

Room temperature