Eriodictyol-7-O-glucoside [CAS 38965-51-4]

Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC50 values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD) -induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO) . Eriodictyol-7-O-glucoside can be used for the study of stroke[1][2][3].

[38965-51-4]

C21H22O11

450.39

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)C=C2O[C@H](C4=CC(O)=C(C=C4)O)C1

Keap1-Nrf2

99.8

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335