Ertugliflozin-d9

Ertugliflozin-d9 is deuterated labeled Ertugliflozin. Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. Has the potential for the treatment of type 2 diabetes mellitus[2].

C22H16D9ClO7

445.94

ClC1=CC=C([C@]23O[C@@](CO)(CO3)[C@@H](O)[C@H](O)[C@H]2O)C=C1CC4=C([2H])C([2H])=C(OC([2H])([2H])C([2H])([2H])[2H])C([2H])=C4[2H]

Isotope-Labeled Compounds; SGLT

SGLT2

10 mM in DMSO

Room temperature