Estromustine [CAS 62899-40-5]

Estromustine (EoM) is the active metabolite of Estramustine phosphate. Estromustine binds to mutant androgen receptor (m-AR) with EC50 of 2.6 μM in LNCaP, exhibits cytotoxicity in human prostate cells LNCaP with IC50 of 9.73 μM[1].

[62899-40-5]

C23H29Cl2NO3

438.39

C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC(N(CCCl)CCCl)=O)C=C4CC3

Androgen Receptor

Room temperature

H302-H315-H319-H335

P261-P280-P302+P352