Ethyl 3,4-Dihydroxybenzoate-13C3 [CAS 1330195-40-8]
Ethyl 3,4-Dihydroxybenzoate-13C3 [CAS 1330195-40-8]
SKU:QM-0054546-01
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Product Details
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Description
Ethyl 3,4-Dihydroxybenzoate-13C3 (Protocatechuic acid ethyl ester-13C3) is the 13C-labeled Ethyl 3,4-dihydroxybenzoate. Ethyl 3,4-dihydroxybenzoate (Protocatechuic acid ethyl ester) is an orally effective, blood-brain barrier-permeable, competitive prolyl hydroxylase (PHD) inhibitor that inhibits the hydroxylation modification of hypoxia-inducible factor (HIF) by PHD. Ethyl 3,4-dihydroxybenzoate stabilizes HIF-1α by inhibiting PHD, activates downstream pathways to induce autophagy and apoptosis of tumor cells, and regulates inflammatory responses, inhibits the NF-κB pathway, improves vascular permeability, and promotes osteoblast differentiation. Ethyl 3,4-dihydroxybenzoate has anti-tumor, anti-hypoxic injury, and bone metabolism regulation effects. It can also be used in the research of cardiovascular protection (such as reducing myocardial ischemic damage), bone tissue engineering (promoting osteogenesis/inhibiting osteoclast differentiation), and prevention and treatment of high-altitude cerebral edema[1][2][3][4].
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CAS Number
[1330195-40-8]
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Molecular Formula
C6 13C3H10O4
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Molecular Weight
185.15
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Smiles
[13CH3][13CH2]O[13C](C1=CC(O)=C(O)C=C1)=O
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Target
Reactive Oxygen Species (ROS)
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Shipping Conditions
Room temperature
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Ethyl 3,4-Dihydroxybenzoate-13C3 [CAS 1330195-40-8]
Ethyl 3,4-Dihydroxybenzoate-13C3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.