Ethynylcytidine [CAS 180300-43-0]
Ethynylcytidine [CAS 180300-43-0]
SKU:QM-0153266-01
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Product Details
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Description
Ethynylcytidine (ECyD), a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer[1][2][3]. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[180300-43-0]
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Molecular Formula
C11H13N3O5
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Molecular Weight
267.24
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Smiles
OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1
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Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
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Concentration
10mM
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Purity
99.97
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Ethynylcytidine [CAS 180300-43-0]
Ethynylcytidine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.