Etrasimod-d9

Etrasimod-d9 (APD334-d9) is a deuterium labeled Etrasimod. Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an IC50 value of 1.88 nM in CHO cells.[1].

C26H17D9F3NO3

466.54

FC(F)(F)C1=CC(COC2=CC=C(NC3=C4CC[C@@H]3CC(O)=O)C4=C2)=CC=C1C5([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C5([2H])[2H]

Isotope-Labeled Compounds; LPL Receptor

Room temperature