EV-A71-IN-1 [CAS 2413648-96-9]

EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM) [1].

[2413648-96-9]

C21H15N5S

369.44

C1(C2=CC=C(C=C2)NC3=NC(C4=CN=C5N=CC=CN45)=CS3)=CC=CC=C1

Enterovirus

10 mM in DMSO

Room temperature