Exo BCN-O-PNB [CAS 1380006-72-3]

Exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

[1380006-72-3]

C17H17NO5

315.32

O=C(OC[C@H]1[C@]2([H])CCC#CCC[C@]12[H])OC3=CC=C([N+]([O-])=O)C=C3

PROTAC Linkers

Alkyl/ether Linkers

98

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335