EXP-7711 [CAS 114798-27-5]

EXP-7711 is a non peptide angiotensin II (Ang II) AT1 receptor antagonist. EXP-7711’s affinity for wild-type AT1 receptor (Ki =180 nM) is lower than peptide antagonists, but higher than losartan (Ki = 12 nM) . EXP-7711 can be used for research on cardiovascular conditions[1].

[114798-27-5]

C22H23ClN2O3

398.88

CCCCC1=NC(Cl)=C(CO)N1CC2=CC=C(C3=C(C=CC=C3)C(O)=O)C=C2

Angiotensin Receptor

AT1 Receptor

Room temperature