FABP4-IN-4

FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models[1].

C25H23N3O5S2

509.6

O=S(C1=C(N=CC=C2)C2=CC=C1)(N3CCN(S(C4=C(C5=CC=CC(O)=C5)C=CC=C4)(=O)=O)CC3)=O

FABP

Room temperature