Fadrozole (hydrochloride hemihydrate) [CAS 176702-70-8]
Fadrozole (hydrochloride hemihydrate) [CAS 176702-70-8]
SKU:QM-0064987-01
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Product Details
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Description
Fadrozole hydrochloride hemihydrate is an orally active, potent, selective and nonsteroidal aromatase inhibitor, with an IC50 of 6.4 nM. Fadrozole hydrochloride hemihydrate inhibits the production of estrogen and progesterone, with IC50 values of 0.03 and 120 μM. Fadrozole hydrochloride hemihydrate shows prevention of spontaneous tumours. Fadrozole hydrochloride hemihydrate can be used for the research of estrogen-dependent disease and cancer[1][2][3].
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CAS Number
[176702-70-8]
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Molecular Formula
C14H13N3.ClH.1/2H2O
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Molecular Weight
268.74
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Smiles
N#CC1=CC=C(C=C1)C2CCCC3=CN=CN23.[H]Cl.[H]O[H].[1/2]
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Target
Cytochrome P450
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Isoform
Aromatase/CYP19A1
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Purity
99.59
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301+H311+H331, H315, H319
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Precautions
H301+H311+H331, H315, H319
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Fadrozole (hydrochloride hemihydrate) [CAS 176702-70-8]
Fadrozole (hydrochloride hemihydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.