FAK-IN-29 [CAS 3104566-26-6]

FAK-IN-29 is a selective FAK inhibitor with an IC50 of 0.5 nM. FAK-IN-29 can inhibit the proliferation and colony formation of MDA-MB-231 cells, and induce cell cycle arrest and apoptosis. FAK-IN-29 exhibits antitumor activity and can be used for the research of tumors such as triple-negative breast cancer[1].

[3104566-26-6]

C26H27FN8O2

502.54

O=C(NC)C1=CC=CC=C1NC2=C3C(NC=C3F)=NC(NC4=CC=CC(CC(N5CCNCC5)=O)=C4)=N2

Apoptosis; FAK

Room temperature