FAK-IN-3 [CAS 2882094-29-1]

FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase (FAK) . FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer[1].

[2882094-29-1]

C28H28N6O4

512.56

COC1=CC(C(NC2CCNCC2)=O)=CC=C1NC3=NC4=C(C(OC5=CC=CC6=C5C(CC6)=O)=N3)C=CN4

FAK

10 mM in DMSO

Room temperature