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Faridoxorubicin [CAS 1841402-73-0]
Faridoxorubicin [CAS 1841402-73-0]
SKU:QM-0014358
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Product Details
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Description
Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα) . Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis) [1].
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CAS Number
[1841402-73-0]
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Molecular Formula
C41H44N4O14
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Molecular Weight
816.81
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Smiles
OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC([C@H]6N(CCC6)C([C@@H](C)NC(C7=CC=NC=C7)=O)=O)=O
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Target
FAP
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Shipping Conditions
Room temperature
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Faridoxorubicin [CAS 1841402-73-0]
Faridoxorubicin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.