Farnesyl pyrophosphate-d3

Farnesyl pyrophosphate-d3 (Farnesyl diphosphate-d3) is a deuterium labeled Farnesyl pyrophosphate. Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

C15H25D3O7P2

385.34

[2H]/C(CC/C(C)=C([2H])/CC/C(C)=C([2H])/COP(O)(OP(O)(O)=O)=O)=C(C)\C

Calcium Channel; Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel

Room temperature