FEN1-IN-6 [CAS 824983-84-8]

FEN1-IN-6 (compound 9) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 23 nM[1].

[824983-84-8]

C12H8N2O5S2

324.33

O=C1NC2=C(C(N1O)=O)SC=C2S(=O)(C3=CC=CC=C3)=O

FLAP

99.67

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature