Fenebrutinib [CAS 1434048-34-6]
Fenebrutinib [CAS 1434048-34-6]
SKU:QM-0155570-01
Couldn't load pickup availability
Request quote or documents
![Fenebrutinib [CAS 1434048-34-6]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research[1].
-
CAS Number
[1434048-34-6]
-
Molecular Formula
C37H44N8O4
-
Molecular Weight
664.8
-
Smiles
O=C1C(NC(C=C2)=NC=C2N3CCN(C4COC4)C[C@@H]3C)=CC(C5=CC=NC(N6C(C7=CC(CC(C)(C)C8)=C8N7CC6)=O)=C5CO)=CN1C
-
Target
Btk
-
Purity
99.89
-
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
-
Storage Conditions
4°C (Powder, stored under nitrogen)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
-
Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
Related Products
- QM-0023228 Velloquercetin [CAS 139955-63-8]
- QM-0021800 Tetrahydroamentoflavone [CAS 48236-96-0]
- QM-0021613-01 Rutin (hydrate) (Standard) [CAS 207671-50-9]
- QM-0006566-01 Tetramethylkaempferol [CAS 16692-52-7]
- QM-0004073-01 β-Naphthoflavone (Standard) [CAS 6051-87-2]
- QM-0112193-01 Recoflavone [CAS 203191-10-0]
- QM-0136391-01 Vecabrutinib [CAS 1510829-06-7]
- QM-0142568-01 Remibrutinib [CAS 1787294-07-8]
- QM-0081297-01 Zanubrutinib [CAS 1691249-45-2]
- QM-0152361-01 Tirabrutinib [CAS 1351636-18-4]
Other industry favorites
- QM-0023228 Velloquercetin [CAS 139955-63-8]
- QM-0021800 Tetrahydroamentoflavone [CAS 48236-96-0]
- QM-0194732-01 Rutin (trihydrate) [CAS 250249-75-3]
- QM-0164103-01 Semilicoisoflavone B [CAS 129280-33-7]
- QM-0097979 Rutin-d3
- QM-0000966 Toxicarol isoflavone [CAS 3044-60-8]
- QM-0164012-01 Sophoraflavanone G [CAS 97938-30-2]
- QM-0162127-01 Troxerutin [CAS 7085-55-4]
- QM-0125886 Taiwanhomoflavone B [CAS 509077-91-2]
- QM-0118153 Sideritoflavone [CAS 70360-12-2]
Fenebrutinib [CAS 1434048-34-6]
Fenebrutinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.