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FGFR-IN-18
FGFR-IN-18
SKU:QM-0011061
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Product Details
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Description
FGFR-IN-18 (Compound KF7) is a lysine-targeting FGFR covalent inhibitor, with IC50s of: 1.1 nM for FGFR2, 1.3 nM for FGFR1, 31.5 nM for FGFR4. FGFR-IN-18 also has affinity for FGFR3 (inhibition rate of 52% at 10 nM) . FGFR-IN-18 covalently modifies Lys485 (an reactive site of FGFRs) [1].
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Molecular Formula
C32H37N9O6
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Molecular Weight
643.69
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Smiles
COC1=CC(CCC2=CC(NC3=NC(NCC4=CC=CC(CNC5=C(C(C5=O)=O)OC)=C4)=NC(NCCOC)=N3)=NN2)=CC(OC)=C1
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Target
FGFR
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Shipping Conditions
Room temperature
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FGFR-IN-18
FGFR-IN-18 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.