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FGFR-IN-19
FGFR-IN-19
SKU:QM-0011062
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Product Details
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Description
Arg-IN-1 is a selective Arginine (Arg) -targeting covalent inhibitor with IC50s of 9.7 nM and 30.4 nM for FGFR2 and FGFR3, respectively. Arg-IN-1 has the potential to avoid FGFR1/4-targeted toxicity as well as conquer acquired on-target resistance, potential for FGFR-targeting cancer therapy[1].
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Molecular Formula
C36H42N12O6
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Molecular Weight
738.8
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Smiles
COCCNC1=NC(NC2=NNC(C3=CC=CC=C3)=C2)=NC(NC4CC5(C4)CCN(CC5)C(CN6C=C(N=N6)COC7=CC=C(C=C7)C(C(O)O)=O)=O)=N1
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Target
FGFR
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Shipping Conditions
Room temperature
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FGFR-IN-19
FGFR-IN-19 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.