FKBP51-Hsp90-IN-2 [CAS 601511-07-3]

FKBP51-Hsp90-IN-2 (Compound E08) is a selective FKBP51-Hsp90 protein-protein interaction inhibitor with IC50 values of 0.4 µM and 5 µM for FKBP51 and FKBP52, respectively. FKBP51-Hsp90-IN-2 also effectively stimulates cellular energy metabolism and neurite growth. FKBP51-Hsp90-IN-2 can be used in research on neurodegenerative diseases and cancer[1].

[601511-07-3]

C25H27N3O2S

433.57

CCC(NC1=C(C=C(C=C1)NC(CSC2=NC3=CC4=C(C=C3C=C2C)CCC4)=O)C)=O

FKBP; HSP

10 mM in DMSO

Room temperature