Fli-1-IN-1 [CAS 3027140-81-1]

Fli-1-IN-1 (compound 21) is a FLI1 targeting agent that directly binds to and inhibits the EWS-FLI1 protein interaction. EWS-FLI1 can bind to RNA helicase A, and Fli-1-IN-1 inhibits EWS-FLI1 and has potential anticancer activity[1].

[3027140-81-1]

C35H44N2O6

588.73

COC1=CC(OC)=C([C@@]2([C@@H](C[C@H]3C4=CC=CC=C4)O)O)C(O[C@]23C(C=C5)=CC=C5OCCCCCN6CCN(C)CC6)=C1

DNA/RNA Synthesis

10 mM in DMSO

Room temperature