FLT3/CHK1-IN-2

Size 1 Each

SKU:QM-0129425

Price on request

Quote Datasheet SDS COA

Product Details

Description
FLT3/CHK1-IN-2 (Compound 30) is a dual inhibitor of FLT3 and CHK1, with IC50s of 25.63, 16.39, 22.80 nM for CHK1, FLT3-WT, and FLT-D835Y respectively. FLT3/CHK1-IN-2 has favorable oral PK properties and kinase selectivity. FLT3/CHK1-IN-2 can be used for research of acute myeloid leukemia (AML) [1].
Molecular Formula
C18H23F3N6O2S
Molecular Weight
444.47
Smiles
NCCCNC1=NC(NC2=CC(CCN(S(=O)(C)=O)C3)=C3C=C2)=NC=C1C(F)(F)F
Target
Checkpoint Kinase (Chk) ; FLT3
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
1 EachQM-0129425	1 EachQM-0129425 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

FLT3/CHK1-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.