Flurocitabine [CAS 37717-21-8]

Flurocitabine (5-Fluorocyclocytidine) is a fluorinated anlydride analog of cytosine arabinoside, partially hydrolysecl in vivo into two active antitumor substances (arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU) ) . Flurocitabine (5-Fluorocyclocytidine) has antitumor activity during phase I studies in acute leukemia and solid tumors[1].

[37717-21-8]

C9H10FN3O4

243.19

O[C@H]1[C@@]2([H])[C@](O[C@@H]1CO)([H])N3C(O2)=NC(C(F)=C3)=N

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature