FM26 [CAS 2407981-35-3]

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SKU:QM-0062109

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Product Details

Description
FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1].
CAS Number
[2407981-35-3]
Molecular Formula
C22H15ClF3N3O3
Molecular Weight
461.82
Smiles
O=C(O)C1=CC=C(NCC2=C(C3=CNC=C3)ON=C2C4=C(C(F)(F)F)C=CC=C4Cl)C=C1
Target
ROR
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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FM26 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.