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Fmoc-Suberol [CAS 212783-75-0]

Fmoc-Suberol [CAS 212783-75-0]

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QM-0185266-01

£51.91 GBP
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Product Details

  • Description

    Fmoc-Suberol is a protein cross-linking agent.

  • CAS Number

    [212783-75-0]

  • Molecular Formula

    C32H27NO5

  • Molecular Weight

    505.56

  • Smiles

    O=C(O)COC1=CC=C(C(NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)C5=CC=CC=C5CC6)C6=C1

  • Target

    Eukaryotic Initiation Factor (eIF)

  • Purity

    98.46

  • Solubility

    10 mM in DMSO

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319, H335

  • Precautions

    P261, P280, P302 + P352, P304 + P340, P305 + P351 + P338
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Fmoc-Suberol [CAS 212783-75-0]

Application Guide

Fmoc-Suberol in Peptide Synthesis & Linker Design

Additional research-use information for Fmoc-Suberol, also known as Ramage Linker, a compound used in Fmoc-SPPS workflows, peptide amide preparation, and linker-development studies.

Fmoc-Suberol is best understood as a Ramage Linker and Fmoc-protected peptide synthesis reagent, rather than as a classical biological target inhibitor. In research workflows, it is relevant for laboratories working on solid-phase peptide synthesis, peptide amide generation, bioconjugation strategy, and spacer/linker design.

The molecule combines an Fmoc-protected amine with an acid-functionalized linker structure. This makes it useful in workflows where researchers need a handle compatible with Fmoc deprotection, downstream coupling chemistry, and controlled linker incorporation during peptide or conjugate development.

SPPS Linker Role

Used in Fmoc-based solid-phase peptide synthesis as a linker reagent for peptide amide and linker-development workflows.

Bioconjugation Utility

Relevant for research involving spacer arm introduction, conjugation design, and linker optimization.

Research-Use Context

Supplied for laboratory and scientific research only, with handling guided by SDS, COA, and local laboratory safety procedures.

Researchers may search for this compound using several related terms, including Fmoc-Suberol CAS 212783-75-0, Ramage Linker, Fmoc Ramage linker, Fmoc-protected linker, and peptide amide linker reagent.

Fmoc-Suberol Ramage Linker CAS 212783-75-0 Fmoc-SPPS linker Peptide amide linker Bioconjugation linker ADC linker research PROTAC linker chemistry

How Researchers Use This Compound

  • Peptide amide synthesis: Used in workflows where a linker strategy is needed for peptide amide preparation under Fmoc-SPPS conditions.
  • Fmoc-based synthesis: The Fmoc protecting group supports compatibility with standard base-labile Fmoc deprotection workflows such as piperidine/DMF.
  • Linker and spacer design: Useful for studies requiring a defined spacer arm or linker scaffold during conjugate design.
  • Bioconjugation research: Relevant to early-stage method development for conjugation, functionalization, and linker optimization.
  • ADC and PROTAC research workflows: Can support linker-design studies where researchers compare spacer length, functional handles, and synthetic compatibility.

Selection Notes for Laboratory Teams

  • Confirm the identity using CAS 212783-75-0, molecular formula C32H27NO5, and PubChem CID 10553577.
  • Review the batch-specific COA for exact purity, assay method, and lot-specific data.
  • Select solvents and reaction conditions according to the synthesis protocol used in the laboratory.
  • Keep the compound tightly sealed and protected from moisture and light during storage and handling.
  • Confirm safety handling, PPE, and disposal requirements using the SDS and local laboratory regulations.

Frequently Asked Questions

What is Fmoc-Suberol used for?

Fmoc-Suberol is used as a linker reagent in solid-phase peptide synthesis, peptide amide synthesis, bioconjugation research, and linker-development workflows.

Is Fmoc-Suberol the same as Ramage Linker?

Yes. Fmoc-Suberol is commonly referred to as Ramage Linker in peptide synthesis and Fmoc-SPPS workflows.

What is the CAS number for Fmoc-Suberol?

The CAS number for Fmoc-Suberol is 212783-75-0.

What is the PubChem CID for Fmoc-Suberol?

The PubChem CID for Fmoc-Suberol is 10553577.

Is Fmoc-Suberol compatible with Fmoc-SPPS?

Yes. Fmoc-Suberol is relevant to Fmoc-based solid-phase peptide synthesis workflows, where base-labile Fmoc deprotection is part of the synthesis strategy.

Is Fmoc-Suberol for research use only?

Yes. Fmoc-Suberol supplied by QuantiMol is intended for laboratory research use only and is not for human, veterinary, food, drug, or household use.

Neutral external references for compound identity, chemical information, and GHS framework:

PubChem CID 10553577 ECHA Chemical Information UN GHS Information