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Fmoc-Val-Cit-PAB-PNP [CAS 863971-53-3]
Fmoc-Val-Cit-PAB-PNP [CAS 863971-53-3]
SKU:QM-0077393-01
£57.09 GBP
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Product Details
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Description
Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers[1][2][3].
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CAS Number
[863971-53-3]
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Molecular Formula
C40H42N6O10
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Molecular Weight
766.8
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Smiles
CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)=O)=O)NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O
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Target
ADC Linker
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Isoform
Cleavable Linker; Protease Cleavable Linker
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Purity
99.6
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Solubility
DMSO : ≥ 40 mg/mL
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Storage Conditions
-20°C (Powder, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Fmoc-Val-Cit-PAB-PNP [CAS 863971-53-3]
Fmoc-Val-Cit-PAB-PNP is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.