Forskolin (GMP) [CAS 66575-29-9]
Forskolin (GMP) [CAS 66575-29-9]
SKU:QM-0070746
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Product Details
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Description
Forskolin (Coleonol) (GMP) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase[1]. Forskolin (GMP) is also an inducer of intracellular cAMP formation[2]. Forskolin (GMP) induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin (GMP) exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin (GMP) also induces autophagy[4][5].
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CAS Number
[66575-29-9]
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Molecular Formula
C22H34O7
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Molecular Weight
410.5
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Smiles
O=C1[C@@]2(O)[C@]([C@@H](OC(C)=O)[C@@H](O)[C@@]3([H])C(C)(C)CC[C@H](O)[C@@]32C)(C)O[C@@](C)(C=C)C1
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Target
Adenylate Cyclase; Autophagy; FXR; PKC
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H312
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Precautions
P280-P302+P352-P362+P364-P501
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Forskolin (GMP) [CAS 66575-29-9]
Forskolin (GMP) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.