Fosamprenavir-13C6
Fosamprenavir-13C6
SKU:QM-0017792
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Product Details
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Description
Fosamprenavir-13C6 is the 13C-labeled Fosamprenavir. Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2][3].
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Molecular Formula
C19 13C6H32N3O9PS
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Molecular Weight
587.53
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Smiles
O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP(O)(O)=O)CN(S(=O)([13C]3=[13C][13C]=[13C](N)[13C]=[13C]3)=O)CC(C)C
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Target
Drug Intermediate; HIV; HIV Protease; Isotope-Labeled Compounds
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Isoform
HIV-1
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Shipping Conditions
Room temperature
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Fosamprenavir-13C6
Fosamprenavir-13C6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.