Fosamprenavir [CAS 226700-79-4]
Fosamprenavir [CAS 226700-79-4]
SKU:QM-0156954-01
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Product Details
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Description
Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir. Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2].
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CAS Number
[226700-79-4]
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Molecular Formula
C25H36N3O9PS
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Molecular Weight
585.61
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Smiles
O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP(O)(O)=O)CN(S(=O)(C3=CC=C(N)C=C3)=O)CC(C)C
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Target
Drug Intermediate; HIV; HIV Protease
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Isoform
HIV-1
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Purity
99.94
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H320
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Precautions
H315, H319, H320
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Fosamprenavir [CAS 226700-79-4]
Fosamprenavir is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.