Fosamprenavir (Calcium Salt) (Standard) [CAS 226700-81-8]
Fosamprenavir (Calcium Salt) (Standard) [CAS 226700-81-8]
SKU:QM-0107170-01
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Product Details
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Description
Fosamprenavir Calcium Salt (GW433908G) (Standard) is the analytical standard of Fosamprenavir Calcium Salt. This product is intended for research and analytical applications. Fosamprenavir Calcium Salt (GW433908G) is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir Calcium Salt is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir Calcium Salt can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2].
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CAS Number
[226700-81-8]
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Molecular Formula
C25H34CaN3O9PS
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Molecular Weight
623.67
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Smiles
O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP([O-])([O-])=O)CN(S(=O)(C3=CC=C(N)C=C3)=O)CC(C)C.[Ca+2]
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Target
Drug Intermediate; HIV; HIV Protease; Reference Standards
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Isoform
HIV-1
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Solubility
H2O : 0.25 mg/mL (ultrasonic; warming)
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Shipping Conditions
Room temperature
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Fosamprenavir (Calcium Salt) (Standard) [CAS 226700-81-8]
Fosamprenavir (Calcium Salt) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.