FPI-1523 [CAS 1452459-50-5]

FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity[1].

[1452459-50-5]

C9H14N4O7S

322.3

CC(NNC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)=O)=O

Bacterial; Beta-lactamase

10 mM in DMSO

Room temperature