FPT [CAS 2048491-06-9]

FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT1AR, a full agonist at 5-HT1BR and 5-HT1DR with EC50s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT7R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models[1].

[2048491-06-9]

C18H20FN

269.36

FC1=C(C=CC=C1)C2=C3C(C[C@H](CC3)N(C)C)=CC=C2

5-HT Receptor

5-HT1 Receptor;5-HT7 Receptor; mLAG-3; MUC3

98.06

DMSO : 66.67 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature