Framycetin [CAS 119-04-0]

Name: Framycetin [CAS 119-04-0]
Brand: QuantiMol
SKU: QM-0154811-01
Price: 78.82 GBP
Availability: InStock

Size 25 mg (16.27 mM x 2.5 mL in 0.9% NaCl) 50 mg (16.27 mM x 5 mL in 0.9% NaCl) 100 mg (16.27 mM x 10 mL in 0.9% NaCl)

SKU:QM-0154811-01

£78.82 GBP

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Product Details

Description
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2].
CAS Number
[119-04-0]
Molecular Formula
C23H46N6O13
Molecular Weight
614.64
Smiles
N[C@@H](C[C@H]1N)[C@@]([C@@H]([C@H]1O)O[C@@](O[C@H](CO)[C@H]2O[C@@]([C@@H]([C@@H](O)[C@@H]3O)N)([H])O[C@H]3CN)([H])[C@@H]2O)([H])O[C@H]([C@@H]([C@@H](O)[C@@H]4O)N)O[C@@H]4CN
Target
Antibiotic; Bacterial
Isoform
Aminoglycoside
Concentration
16.27 mM * 2.5 mL in 0.9% NaCl
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Storage Conditions
Solution, -20°C, 2 years
Shipping Conditions
Blue Ice
Hazard Statement
H317, H334
Precautions
H317, H334

Your cart
Variant	Variant total	Quantity	Price	Variant total
25 mg (16.27 mM x 2.5 mL in 0.9% NaCl)QM-0154811-01	25 mg (16.27 mM x 2.5 mL in 0.9% NaCl)QM-0154811-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

50 mg (16.27 mM x 5 mL in 0.9% NaCl)QM-0154811-02	50 mg (16.27 mM x 5 mL in 0.9% NaCl)QM-0154811-02 £118.38/ea	£0.00	Quantity	£118.38/ea	£0.00

100 mg (16.27 mM x 10 mL in 0.9% NaCl)QM-0154811-03	100 mg (16.27 mM x 10 mL in 0.9% NaCl)QM-0154811-03 £188.51/ea	£0.00	Quantity	£188.51/ea	£0.00

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Framycetin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.