FStAx-35R (TFA)

FStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research[1].

C136H198N42O27S.xC2HF3O2

O=C([C@H](CCCNC(N)=N)NC(COCCOCCNC(NC1=CC2=C(C3(OC2=O)C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)C=C1)=S)=O)N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C(N8CCC[C@H]8C(N[C@@H](CCCNC(N)=N)C(N[C@](C)(C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H]9CC(O)=O)=O)=O)=O)CCC/C=C/CCC[C@@](C)(C(N[C@@H](CC%10=CN=CN%10)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC%11=CNC%12=C%11C=CC=C%12)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]

Wnt; β-catenin

97.35

DMSO : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice