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SKU:QM-0140812-01
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FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
[344900-92-1]
C25H30N4O3S
466.6
CSCC[C@@H](C(OC)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O
Farnesyl Transferase
99.77
DMSO : 90 mg/mL (ultrasonic; warming)
-20°C (Powder, stored under nitrogen)
Blue Ice
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FTI-2153 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.