FTO-IN-13 [CAS 687600-25-5]

FTO-IN-13 (compound 8t) is a potent FTO inhibitor. FTO-IN-13 shows antiproliferative activity. FTO-IN-13 induces apoptosis. FTO-IN-13 decreases the protein expression of Bcl-2 and Caspase 3 active. FTO-IN-13 decreases MYC and CEBPA gene expression. FTO-IN-13 shows anticancer activity[1].

[687600-25-5]

C18H12Br2N2O4

480.11

O=C(C1=CC2=C(C=C1O)C=CC=C2)N/N=C/C3=CC(Br)=C(C(Br)=C3O)O

Apoptosis; Fat Mass and Obesity-associated Protein (FTO)

Room temperature