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FW-1

FW-1

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SKU:QM-0009417

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  • Description

    FW-1 is a type I inhibitor for FLT3 with IC50 of ca. 1 μM. FW-1 exhibits cytotoxicity in FLT3 mutated AML cell. FW-1 arrests the cell cycle at G0/G1 phase, and induces apoptosis in cell MV4-11 and MOLM-13[1].

  • Molecular Formula

    C24H27N7O

  • Molecular Weight

    429.52

  • Smiles

    NC1=NOC2=NC(NC3=CC=C(CN4CCN(C)CC4)C=C3)=CC(NC5=CC=CC=C5)=C21

  • Target

    Apoptosis; FLT3

  • Shipping Conditions

    Room temperature

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FW-1

FW-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.