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FW-1
FW-1
SKU:QM-0009417
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Product Details
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Description
FW-1 is a type I inhibitor for FLT3 with IC50 of ca. 1 μM. FW-1 exhibits cytotoxicity in FLT3 mutated AML cell. FW-1 arrests the cell cycle at G0/G1 phase, and induces apoptosis in cell MV4-11 and MOLM-13[1].
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Molecular Formula
C24H27N7O
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Molecular Weight
429.52
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Smiles
NC1=NOC2=NC(NC3=CC=C(CN4CCN(C)CC4)C=C3)=CC(NC5=CC=CC=C5)=C21
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Target
Apoptosis; FLT3
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Shipping Conditions
Room temperature
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FW-1
FW-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.