FXa-IN-1 [CAS 441328-10-5]

FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders[1].

[441328-10-5]

C24H18F5N5O

487.42

O=C(NC1=CC=C(C(N(C)C)=N)C=C1F)C2=CC(C(F)(F)F)=NN2C3=C(F)C=C(C=CC=C4)C4=C3

Factor Xa

10 mM in DMSO

Room temperature